IN A MULTICENTER, RANDOMIZED PARALLEL-GROUP STUDY OF 782 ADULTS WITH ASTHMA WHO RECEIVED SIX WEEKS OF DOUBLE-BLIND TREATMENT, SINGULAIR PROVIDED EFFICACY COMPARABLE TO AN INHALED STEROID15a
Results shown in graph are modified from study report of 97+0.9%, 96.1+1%, and 91.9+2.6%, respectively, with asthma attacks. Adapted from Israel E et al J Allergy Clin Immunol 2002;110(6):847–854.
See Study Design A
NO SIGNIFICANT DIFFERENCE BETWEEN SINGULAIR AND BECLOMETHASONE GROUPS IN:
bid=twice daily a Double-blind treatment consisted of SINGULAIR 10 mg once daily in the evening, beclomethasone 200 µg twice daily, or placebo.15 bp=0.488 for SINGULAIR vs. beclomethasone15 cAn asthma control day was defined as a day with two or less inhalations of albuterol (including those for exercise prophylaxis), no nighttime awakenings, and no asthma attacks. An asthma attack was defined as worsening asthma resulting in an unscheduled visit to the doctor's office or an emergency department, hospitalization, or treatment with oral corticosteroids.15
